Is There a Maximum Age for IVF?

Is There a Maximum Age for IVF?

In vitro fertilization is the method of transferring eggs collected from the ovaries and activated by IVF drugs into the uterus after fertilization in a laboratory environment. The age of the woman is the most important factor affecting the success of IVF.

What is the importance of age in IVF?

Women have 2 million eggs in their ovaries at birth. It decreases until adolescence, when it drops to 250 thousand levels. After this period, 1-2 eggs are laid in each menstrual pay period, and the growth of many eggs ceases and fades. Until the age of 35, the quantity of eggs gradually falls. However, after the age of 35, the rate of egg reduction accelerates, resulting in fast egg loss in women. As a result, it is advised that women avoid delaying pregnancy, especially after the age of 35.

The number of eggs in the ovary decreases as us approach menopause, and there are no eggs in the ovary when we reach menopause. In Turkey, the average age of menopause is 47 years. However, some women may experience menopause before the age of 40. (premature menopause).

Is There a Maximum Age for IVF?

How does a woman's age affect the success of IVF treatment?

Women's fertility rates are highest between the ages of 24 and 34. The possibility to become pregnant gradually declines beyond the age of 35. While the probability of pregnancy is 30% between the ages of 35 and 40, it is 10-20% between the ages of 40 and 45, and fewer than 5% in those who do IVF at the age of 45. The quantity of eggs produced by women and the quality of their eggs are two parameters that influence the outcome of IVF treatment. Unfortunately, as women get older, both the amount and quality of their eggs diminish. A decrease in the number and quality of eggs indicates a decrease in pregnancy potential. Despite the use of greater medication doses in elderly women, eggs do not always develop. Again, as one gets older, the rate of fertilization and the rate of embryo attachment to the uterus slow down. Furthermore, certain age-related uterine deformities (fibroids, polyps, endometriosis, and so on) or disorders will diminish the likelihood of pregnancy.

The quality of the embryo developed as a result of the drop in egg quality falls, particularly in women over the age of 40. While a decline in embryo quality reduces the likelihood of conception, it also raises the risk of miscarriage in those who become pregnant. As a result, using preimplantation genetic diagnosis (PGD) and the greatest quality embryos in in vitro fertilization in women over 40 years old will enhance the possibility of pregnancy while decreasing the risk of abnormality and miscarriage in the infant. However, the use of PGD on all patients beyond the age of 40 is still debatable. For men, there is no established age limit. Men's sperm production never stops.

On the third day of menstruation, ultrasonography and hormone testing are used to estimate ovarian reserves in women seeking IVF treatment. All of these factors are considered, together with the woman's age, to decide the appropriate treatment.

In light of this information, it is advised that women do not postpone pregnancy. It should be remembered that the quantity of eggs in the ovaries significantly declines after the age of 35. Those over the age of 40 who have IVF are less likely to become pregnant. It is less than 5% beyond the age of 45. If you postpone your pregnancy for a variety of reasons, you may face lengthy and onerous processes later on.

Can IVF Treatment Usually Be done Up to What Age?

Age restrictions in IVF treatment vary from country to country and from clinic to clinic; however, there is no legal age limit. The IVF treatment process, which started in the 1970s, began to be discussed in the medical world and religious circles. When a woman is born, she has about 6-7 million eggs; By the age of 30, she loses about 90% of her eggs, and by age 40, only 3% of her eggs remain.

Today, most women can get pregnant in their mid-40s. Advances in assisted reproductive techniques, such as in vitro fertilization, are expanding the boundaries of reproduction. However, as a woman gets older; The risk of dangerous complications related to the child and childbirth also increases significantly.

The Age of Patients is an Important Criterion for  IVF Treatment Success!

The ability of a woman to become pregnant slowly declines until the age of 40, when it drastically declines. Around the age of 28, a woman's fertility begins to drop. The decline curve steepens at age 35 and accelerates slightly between ages 39 and 42. Almost often, a woman's chances of naturally conceiving are greatly reduced, on average, 10 years before menopause.

Healthy and fertile women over the age of 30 have a 20% chance of conceiving. Experts estimate that by the age of 40, a woman's chances of conceiving are roughly 5%. It all comes down to the quality and amount of eggs. Women are born with all of their eggs.

Furthermore, even during her most reproductive years, a woman has half of her eggs with chromosomal abnormalities, and the number of eggs with genetic issues grows with age. Fertile eggs eventually become nearly extinct, and this occurs earlier in certain women.

With IVF Treatment, it is Possible to Become a 45-year-old Mother!

There have been significant advances, especially in embryo and egg freezing. He can now freeze embryos one at a time, and when we thaw them, about 99 percent of them are still alive. In patients whose uterus is not functioning properly, whose hormones are not responding, and who are experiencing difficulties during treatment, we have the option to freeze the embryo at any time without hesitation and thaw it when the opportunity is optimal. Aside from that, the advancement of the medium fluids we employ in the laboratory allows us to transport the embryos to the 5th day more readily. Embryos that have reached the 5th day have a higher likelihood of connecting to the uterus than embryos that have reached the 3rd day. Our pregnancy rates have increased significantly as a result of this. The advancement of technology in the realm of health continues to bring hope for the treatment of many disorders. In vitro fertilization treatment, particularly egg and embryo freezing, is an essential field impacted by technology.